Since the report of the initial outbreak of the disease, only one fulllength genome from a strain isolated in 1984 porpvlpmv1984 has been sequenced. All structured data from the file and property namespaces is available under the creative commons cc0 license. Las alteraciones reproductivas en sementales incluyen epididimitis y atrofia testicular. Cuevasromero s1, blomstrom al, alvarado a, hernandezjauregui p, riverabenitez f, ramirezmendoza h, berg m. In immunofluorescence assays using a monoclonal antibody mab against the hn protein at 560 min postinfection early infection, a diffuse immunofluorescence was observed near the cell membrane and adjacent to the nuclear membrane. Rubulavirus is a descriptor in the national library of medicines controlled vocabulary thesaurus, mesh medical subject headings. Porcine rubulavirus definition of porcine rubulavirus by. Porcine rubulavirus infection, or blue eye disease, is an illness that has been reported only from mexico. Purification of porcine rubulavirus attachment protein by isoelectric focusing.
Blue eye disease is typically characterized by encephalitis, respiratory disease and high. A read is counted each time someone views a publication summary such as the title, abstract, and list of authors, clicks on a figure, or views or downloads the fulltext. Files are available under licenses specified on their description page. Enfermedad del ojo azul by iowa state university center for. Porcine rubulavirus porpv infection emerged spontaneously in pigs in mexico in the early 1980s. Examples of paramyxovirinae genera include rubulavirus, which is composed of several species of human parainfluenza viruses and the mumps viruses. The v protein blocks also the type i and ii interferon signaling pathways by interacting with and inhibiting host stat1 and stat2. The neurovirulence of the new isolates maintains similar characteristics to those reported more than 30 years ago. Help pages, faqs, uniprotkb manual, documents, news archive and biocuration projects. Humans, apes, pigs, and dogs serve as natural hosts. Author links open overlay panel pablo hernandezjauregui a b alia yacoub a seamus kennedy c bill curran c carlos tellez b martin svenda a leif ljung d jorge morenolopez a.
Etiology porcine rubulavirus porv is an enveloped rna virus in the genus rubulavirus, family paramyxoviridae. Feb 29, 2016 porcine rubulavirus porpv and swine influenza virus infection causes respiratory disease in pigs. Development of a realtime rtpcr method for detection of. Porcine rubulavirus infection iowa state university. Rubulavirus porcino, virus lpm, sindrome del ojo azul, virus. The v protein plays a role in inhibition of mda5 antiviral signaling. Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity. Punctate immunofluorescence was apparent at the external surface of the cytoplasmic membrane when lpmvinfected pk15 cells were incubated with the mab against the hn protein of lpmv 5 min p. Respiratory disease in growing pigs after porcine rubulavirus experimental. Structurefunction analysis of two variants of mumps virus hemagglutininneuraminidase protein purification and characterization of the hemagglutininneuraminidase of porcine rubulavirus lpmv. Mar 05, 2015 this page was last edited on 7 march 2015, at 09. Porcine rubulavirus article about porcine rubulavirus by.
Genetic and antigenic changes in porcine rubulavirus ncbi. No immunofluorescence was seen in cells when the primary mab was omitted, or in mockinfected cells. The disease is generally mild, but in some cases can be associated with. Hostvirus interaction inhibition of host interferon induction. This virus, which affects pigs, first emerged in the 1980s and has since become a serious concern for the mexican swine industry.
Rubulavirinae is a subfamily of viruses in the family paramyxoviridae. Molecular characterization of the hemagglutininneuraminidase. Porpv persistent infection could facilitate the establishment of secondary infections. Respiratory disease in growing pigs after porcine rubulavirus. Development of a realtime rtpcr method for detection of porcine rubulavirus porv lpmv.
Achimota rubulavirus 1 achimota rubulavirus 2 bat mumps rubulavirus human rubulavirus 2 human rubulavirus 4 mammalian rubulavirus 5 mapuera rubulavirus menangle rubulavirus mumps rubulavirus porcine rubulavirus simian rubulavirus sosuga rubulavirus teviot rubulavirus tioman. The aim of this study was to analyse the pathogenicity of classic swine h1n1 influenza virus swh1n1 in growing pigs persistently infected with porcine. Rubulavirus definition of rubulavirus by medical dictionary. There are currently 17 species in the two genera orthorubulavirus and pararubulavirus. Mumps is a contagious vaccinepreventable disease, caused by mumps virus muv, a member of the family paramyxoviridae.
There are five subgroups classified based on the hemagglutininneuraminidase hn gene. Porcine rubulavirusla piedadmichoacanmexico virus porpvlpmv was identified as the causative agent of a viral disease that emerged. Feb 29, 2016 read coinfection of classic swine h1n1 influenza virus in pigs persistently infected with porcine rubulavirus, veterinary microbiology on deepdyve, the largest online rental service for scholarly research with thousands of academic publications available at your fingertips. Blue eye disease, caused by a porcine rubulavirus porv, is an emergent viral swine disease that has been endemic in mexico since 1980. Experimental infection with recent porcine rubulavirus strains causes acute neurologic disease in pigs viral distribution were identified in nervous, lymphatic, and respiratory systems of the piglets. Molecular and epidemiological studies of porcine rubulavirus. Sv5 is a species of the genus rubulavirus which also contains mumps virus and human parainfluenza virus 4 fauquet, 2005. Avulavirus, which contains the species newcastle disease virus of poultry as well as various avian paramyxoviruses. Coinfection of classic swine h1n1 influenza virus in pigs.
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